Introducción: Los biomarcadores son útiles en la definición del diagnóstico, pronóstico y seguimiento de múltiples enfermedades. La detección o medición de uno o más biomarcadores específicos representan alteraciones en vías genéticas o epigenéticas que controlan la proliferación, diferenci...
Helsingen, Lise M;
Vandvik, Per Olav;
Jodal, Henriette C;
Agoritsas, Thomas;
Lytvyn, Lyubov;
Anderson, Joseph C;
Auer, Reto;
Murphy, Silje Bjerkelund;
Almadi, Majid Abdulrahman;
Corley, Douglas A;
Quinlan, Casey;
Fuchs, Jonathan M;
McKinnon, Annette;
Qaseem, Amir;
Heen, Anja Fog;
Siemieniuk, Reed A C;
Kalager, Mette;
Usher-Smith, Juliet A;
Lansdorp-Vogelaar, Iris;
Bretthauer, Michael;
Guyatt, Gordon.
Recent 15-year updates of sigmoidoscopy screening trials provide new evidence on the effectiveness of colorectal cancer screening. Prompted by the new evidence, we asked: “Does colorectal cancer screening make an important difference to health outcomes in individuals initiating screening at age 50 to 7...
Shroff, Rukshana;
Calder, Francis;
Bakkaloglu, Sevcan;
Nagler, Evi V;
Stuart, Sam;
Stronach, Lynsey;
P. Schmitt, Claus;
H. Heckert, Karl;
Bourquelot, Pierre;
Wagner, Ann-Marie;
Paglialonga, Fabio;
Mitra, Sandip;
Stefanidis, Constantinos J.
There are three principle forms of vascular access available for the treatment of children with end stage kidney
disease (ESKD) by haemodialysis: tunnelled catheters placed in a central vein (central venous lines, CVLs), arteriovenous fistulas (AVF), and arteriovenous grafts (AVG) using prosthetic orbiol...
This guideline covers recognising, diagnosing and managing attention deficit hyperactivity disorder
(ADHD) in children, young people and adults. It aims to improve recognition and diagnosis, as well
as the quality of care and support for people with ADHD.
In September 2019 we amended the recommendation o...
Ergan, B;
Oczkowski, S;
Rochwerg, B;
Carlucci, A;
Chatwin, M;
Clini, E;
Elliott, M;
Gonzalez-Bermejo, J;
Hart, N;
Lujan, M;
Nasilowski, J;
Nava, S;
Pepin, J. L;
Pisani, L;
Storre, J. H;
Wijkstra, P;
Tonia, T;
Boyd, J;
Scala, R;
Windisch, W.
While the role of acute non-invasive ventilation (NIV) has been shown to improve outcome in acute life-threatening hypercapnic respiratory failure in COPD, the evidence of clinical efficacy of long-term home NIV (LTH-NIV) for management of COPD is less. This document provides evidence-based recommendatio...
Holguin, Fernando;
Cardet, Juan Carlos;
Chung, Kian Fan;
Diver, Sarah;
Ferreira, Diogenes S;
Fitzpatrick, Anne;
Gaga, Mina;
Kellermeye, Liz;
Khurana, Sandhya;
Knight, Shandra;
McDonald, Vanessa M;
Morgan, Rebecca L;
Ortega, Victor E;
Rigau, David;
Subbarao, Padmaja;
Tonia, Thomy;
Adcock, Ian M;
Bleecker, Eugene R;
Brightling, Chris;
Boulet, Louis-Philippe;
Cabana, Michael;
Castro, Mario;
Hamerlijnck, Dominique;
Jarjour, Nizar;
Konno, Satoshi;
Shen, Huahao;
Vitary, Cathy;
Bush, Andy.
This document provides clinical recommendations for the management of severe asthma. Comprehensive evidence syntheses, including meta-analyses, were performed to summarise all available evidence relevant to the Task Force's questions. The evidence was appraised using the Grading of Recommendations, Asses...
Duijts, Liesbeth;
van Meel, Evelien R;
Moschino, Laura;
Baraldi, Eugenio;
Barnhoorn, Magda;
Bramer, Wichor M;
Bolton, Charlotte E;
Boyd, Jeanette;
Buchvald, Frederik;
del Cerro, Maria Jesus;
Colin, Andrew A;
Ersu, Refika;
Greenough, Anne;
Halvorsen, Thomas;
Gremmen, Christiaan;
Kamphuis, Juliette;
Kotecha, Sailesh;
Rooney-Otero, Kathleen;
Schulzke, Sven;
Wilson, Andrew;
Rigau, David;
Morgan, Rebecca L;
Tonia, Thomy;
Roehr, Charles C;
Pijnenburg, Marielle W.
This document provides recommendations for monitoring and treatment of children in whom bronchopulmonary dysplasia (BPD) has been established and were discharged from the hospital, or who were older than 36 weeks of postmenstrual age. The guideline was based on pre-defined Population, Intervention, Com...
This guideline covers interventions in secondary and further education to prevent and reduce
alcohol use among children and young people aged 11 up to and including 18. It also covers people
aged 11 to 25 with special educational needs or disabilities in full-time education. It will also be
relevant to c...
Panaccione, R;
Steinhart, A. H;
Bressler, B;
Khanna, R;
Marshall, J. K;
Targownik, L;
Bitton, A;
Borgaonkr, M;
Chauhan, U;
Halloran, B;
Jones, J;
Kennedy, E;
Leontiadis, G. I;
Jr Loftus, E. V;
Meddings, J;
Moayyedi, P;
Plamondon, S.
Crohn's disease (CD) is a lifelong illness with substantial morbidity, although new therapies and treatment paradigms have been developed. We provide guidance for treatment of ambulatory patients with mild to severe active luminal CD. We performed a systematic review to identify published studies of the ...
Liu, Rong;
Wakabayashi, Go;
Palanivelu, Chinnusamy;
Tsung, Allan;
Yang, Kehu;
Goh, Brian K. P;
Ching-Ning Chong, Charing;
Moo Kang, Chang;
Peng, Chenghong;
Kakiashvili, Eli;
Han, Ho-Seong;
Kim, Hong-Jin;
Takaori, Kyoichi;
Marino, Marco Vito;
Wang, Shen-Nien;
Guo, Tiankang;
Hackert, Thilo;
Huang, Ting-Shuo;
Anusak, Yiengpruksawan;
Fong, Yuman;
Nagakawa, Yuichi;
Shyr, Yi-Ming;
Wu, Yao-Ming;
Zhao, Yupei;
He, Jin;
Lee, Jae Hoon.
The robotic surgical system has been applied to various types of pancreatic surgery. However, controversies exist regarding a variety of factors including the safety, feasibility, efficacy, and cost-effectiveness of robotic surgery. This study aimed to evaluate the current status of robotic pancreatic su...
